The Relationship Tips
Take a fresh look at your lifestyle.

Consume plant-based diet for healthy heart: Study


Washington: Following a plant-based diet and cutting down on consumption of animal products can reduce the risk of heart diseases, suggests a new study.

Consuming plant-based diet functions by minimising the adverse effects of a gut-microbiome associated with an increased risk of coronary heart disease.

The study was published in the journal of the American College of Cardiology.

The body’s gut microbiota is comprised of a series of microbes that play an important role in our metabolism, nutrient absorption, energy levels, and immune response.

A gut-microbiota related metabolite known as trimethylamine N-oxide (TMAO) is produced when gut bacteria digest nutrients commonly found in animal products such as red meat.

It has been connected to increased heart attack and coronary heart disease (CHD) risk. Maintaining a vegan or vegetarian diet has been found to reduce the amount of TMAO produced in the body.

The study authors examined 760 women in the Nurses’ Health Study, a prospective cohort study of 121,701 female registered nurses aged 30 to 55 years old.


Women were asked to report data on dietary patterns, smoking habit, and physical activity, plus other demographic data and provide two blood samples taken at Cleveland Clinic, 10 years apart.

The researchers measured plasma concentrations of TMAO from the first collection to the second blood collection.

After adjusting for participants with available plasma TMAO levels at both collections, there were 380 cases of CHD and 380 demographically matched-control participants without CHD chosen by the researchers included in the analysis.

The risk of CHD was calculated by changes in TMAO levels in the body throughout the follow-up period. Assessing TMAO levels relies on diet and nutrient intake; the researchers investigated how diet quality modifies the association between TMAO and CHD.

Women who developed CHD had higher concentrations of TMAO levels, higher BMI, a family history of heart attack and did not follow a healthy diet including a higher intake of vegetables and a lower intake of animal products.

Women with the largest increases in TMAO levels across the study had a 67 percent higher risk of CHD.

“Diet is one of the most important modifiable risk factors to control TMAO levels in the body. No previous prospective cohort study has addressed whether long-term changes in TMAO are associated with CHD and whether dietary intakes can modify these associations,” said the researcher Lu Qi.
“Our findings show that decreasing TMAO levels may contribute to reducing the risk of CHD, and suggest that gut-microbiomes may be new areas to explore in heart disease prevention,” added Lu Qi.

Leave A Reply

Your email address will not be published.

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More